The National BioResource Project for the Rat in Japan

Strain information

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NBRP Rat No: 0004
Strain name: DON/Kyo
Commmon Name: DON, Donryu rat, DONRYU
Principal Investigator:
Tadao SerikawaGraduate School of Medicine, Kyoto University
Preservation Status:
Coat Color
albino (c)
Inbred Generations
F64+64 (March 2012)
../images/Photos/DON/132a%20(Large).jpg../images/Photos/DON/132z%20(Large).jpg
Usage Restrictions
Genetic Status
Comercial Availability
Research Category
Gene Affected
Origin
Japanese albino rats > R.Sato, Nippon Rat(1950) > Kyo (1978, F64), formaly DONRYU/2
Strain characteristics
Japanese reference strain.
Breeding Conditions
Good breeding performance.
Genotyping
References
Niiya K, Ohara H, Isono M, Sheikh AM, Matsuo H, Fujikawa K, Isomura M, Kato N, Nabika T.
Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat.
Sci Rep. 2018 Jun 20;8(1):9403.

Igarashi M, Hippo Y, Ochiai M, Fukuda H, Nakagama H.
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Biochem Biophys Res Commun. 2013 Dec 13. pii: S0006-291X(13)02128-1.

Hirayama et al.,
Genetic profile of 12 inbred rat strains for 46 microsatellite loci selected as genetic monitoring markers.
Jikken Dobutsu. 43(1),129-132, 1994.

Yamada J.
Genetic markers in the rat: importance of inbred strains and Donryu rat.
Igaku & Yakugaku 4(5):599-606,1980. (Japanese)
Additional strain information (Japanese only)