Strain information  NBRP Rat No: 0076  Strain name: WKAH.LEC-Atp7bhts/Tj  Commmon Name: WKAH.C-hts Rat Genome Database Principal Investigator:  Kozo Matsumoto  The University of Tokushima Graduate School of Medicine       3-18-15 Kuramoto-cho    770-8503 Tokushima     JAPAN Tel: 088-633-9278    Fax: 088-600-9429 Email: kozo@anex.med.tokushima-u.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color   Inbred Generations  N8F46 Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The RECIPIENT must agree on collaborative research with the DEPOSITOR. Any form of publications of data resulting from the use of the BIOROGICAL RESOURCE require co-authorship. This condition is NOT limited to two-year period after deposition. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Atp7b: ATPase, Cu++ transporting, beta polypeptide Origin A congenic strain produced by 8 generation backcrosses to WKAH strain in 1989. Strain characteristics hepatitis, hepatoma Breeding Conditions Good breeding performance. Genotyping References Minami T, Kaneda S, Otsuka T, Jiao Z, Suzuki Y, Yamada T, Matsumoto K, Izumi K. Role of Atp7b gene in spontaneous and N-diethylnitrosamine-induced carcinogenesis in a new congenic strain, WKAH.C-Atp7b rats. Jpn J Cancer Res. 2001 Aug;92(8):841-7. Additional strain information WKAH