Strain information
 NBRP Rat No: 0077  Strain name: WKAH.LEC-Ptprkthid/Tj  Commmon Name: WKAH.C-thid Rat Genome Database
Principal Investigator:  Kozo Matsumoto  The University of Tokushima Graduate School of Medicine       3-18-15 Kuramoto-cho    770-8503 Tokushima     JAPAN
Tel: 088-633-9278    Fax: 088-600-9429 Email: kozo@anex.med.tokushima-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/ ../images/Photos/
Coat Color  
Inbred Generations  N8F41
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT must agree on collaborative research with the DEPOSITOR. Any form of publications of data resulting from the use of the BIOROGICAL RESOURCE require co-authorship. This condition is NOT limited to two-year period after deposition.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected Ptprk: protein tyrosine phosphatase, receptor type, K, extracellular region
Origin A congenic strain produced by 8 generation backcrosses to WKAH strain in 1989.
Strain characteristics a defect of T cell maturation
Breeding Conditions Good breeding performance.
Genotyping
References Chai JG, Sakai T, Hisaeda H, Nagasawa H, Yasutomo K, Furukawa A, Ishikawa H, Maekawa Y, Uehara H, Izumi K, Matsumoto K, Himeno K.
Development of functional rat-derived T cells in SCID mice engrafted with the fetal thymus of LEC rats which are defective in CD4+ T cells.
Microbiol Immunol. 1996;40(9):659-64.
Additional strain information WKAH