Strain information
NBRP Rat No: 0707
Strain name
: SHR.SHRSP-(
D1Rat93-D1Rat269
)(
D18Rat73-D18Rat11
)/Izm
Commmon Name: SHRpch1_18
Rat Genome Database
Principal Investigator:
Tohru Nabika Shimane University, School of Medicine 89-1 Enya-cho, Izumo 693-8901 Shimane Japan
Tel: 0853-20-2136 Fax: 0853-20-2135
Email: nabika@med.shimane-u.ac.jp
Preservation Status:
Embryo
Sperm
Living Animals
Coat Color
白
Inbred Generations
F11
Usage Restrictions
Recipients are requested to obtain a written approval of the depositor.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Origin
A double congenic strain made by introducing segments of chromosome 1 and 18 from SHRSP/Izm into SHR/Izm.
Strain characteristics
Hypertension (as severe as SHR rat) This rat develops a stroke caused by salt loading at an early stage.
Breeding Conditions
Genotyping
References
Yamagata K, Yamamoto M, Kawakami K, Ohara H, Nabika T.
Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
Neuroscience. 267:277-285, 2014.
Additional strain information