Strain information
 NBRP Rat No: 0709  Strain name: SHRSP.SHR-(D1Mgh5-D1Got87)/Izm  Commmon Name: SPrch1.10 Rat Genome Database
Principal Investigator:  Tohru Nabika  Shimane University, School of Medicine       89-1 Enya-cho, Izumo    693-8901 Shimane     Japan
Tel: 0853-20-2136    Fax: 0853-20-2135 Email: nabika@med.shimane-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  
Inbred Generations  F11
Usage Restrictions  Recipients are requested to obtain a written approval of the depositor.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin A congenic strain made by introducing a segments of chromosome 1 from SHR/Izm into SHRSP/Izm.
Strain characteristics Hypertension. This rat has less incidence of a stroke caused by salt loading than SHRSP rat.
Breeding Conditions
Genotyping
References A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains.
Wang M, Ohara H, Egawa M, Fukunaga S, Matsuo H, Ge ZR, Nabika T.
Exp Anim. 2022 Mar 29. doi: 10.1538/expanim.21-0189. Online ahead of print.
Additional strain information