Strain information
 NBRP Rat No: 0728  Strain name: SHR/2Kpo  Commmon Name: SHR, SHR-C/Kpo Rat Genome Database
Principal Investigator:  Yoshio Ohta  Nara Hospital Kinki University Faculty of Medicine       Otoda-cho, Ikoma-shi,    630-0293 Nara     Japan
Tel: 074-377-0880    Fax:  Email: ohta@nara.med.kindai.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  アルビノ
Inbred Generations  F163
Usage Restrictions  The RECIPIENT must specify that SHR/2Kpo strain was bred and maintained at Kinki University Faculty of Medicine.
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin Spontaneously hypertensive rat (SHR) was segregated in Wistar-Kyoto rat in 1963.
Strain characteristics systolic blood pressure: ～200 mmHg in male and 190 mmHg in female
Breeding Conditions Good breeding performance
Genotyping
References 1. Okamoto K. Experimental studies on the relationship between endocrine organs and hypertension.
Nippon Naibunpi Gakkai Zasshi 1962; 38: 782-794.(Japanese)
2.Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Circ J 1963; 27: 282-293.
3. Okamoto K. Spontaneous hypertensive rats. Richter GW, Epstein MA eds. Intern review of experimental
Pathology, New York and London: Academic Press, 1969; 7: 227-270.
4.Okamoto K. Yamori Y, Ooshima a, et al. Establishment of the inbred strain of the spontaneously
hypertensive rat and genetic gactors in volved in hypertension. Okamoto K ed. Spontaneous hypertension:
its pathogenesis and complications. Tokyo: Igaku Shoin, 1972; 1-8.
Additional strain information