Strain information  NBRP Rat No: 0027  Strain name: KND/Tky  Commmon Name: KND, Komeda non-diabetic rat Rat Genome Database Principal Investigator:  Eiichi Kawamoto  Tokyo Medical University       6-1-1 Shinjuku, Shinjuku-ku,    160-8402 Tokyo     JAPAN Tel: 03-3351-6141    Fax: 03-3350-8689 Email: kawamoto@tokyo-med.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  black hooded (a,B,C,h) Inbred Generations  F23+39 Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Japan SLC,Inc. Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin Komeda diabetes-prone rat developed by Komeda from Long-Evans Tokushima Lean (LETL) rat at Tokyo Medical College in 1996. Komeda non Diabetic Rats were established simultaneusely as controls. Strain characteristics Control strain for KDP rat (NBRP No.0026). Breeding Conditions Sib mating. Genotyping References Yokoi N, Komeda K, Wang HY, Yano H, Kitada K, Saitoh Y, Seino Y, Yasuda K, Serikawa T, Seino S. Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet. 31(4):391-4, 2002 Komeda K, Noda M, Terao K, Kuzuya N, Kanazawa M, Kanazawa Y. Establishment of two substrains, diabetes-prone and non-diabetic, from Long-Evans Tokushima Lean (LETL) rats. Endocr J. 45(6):737-44, 1998 Additional strain information KND