Strain information  NBRP Rat No: 0005  Strain name: F344.ACI-Lmx1aqc/Kyo  Commmon Name: F344.ACI-Lmx1aqc, Queue courte rats Rat Genome Database Principal Investigator:  Tadao Serikawa  Graduate School of Medicine, Kyoto University       Yoshidakonoe-cho, Sakyo-ku    606-8501 Kyoto     JAPAN Tel: 075-753-4360    Fax: 075-753-4409 Email: serikawa@anim.med.kyoto-u.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  N13F11 (May 2009) Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Lmx1a: LIM homeobox transcription factor 1 alpha Origin From ACI/Pas stock in Institute Pasteur, France. After 1998 introduced to Kyoto University, F344/NSlc backgrund congenic rats were established at Kyoto University. Strain characteristics short tail, neurologic disorder similar to dreher mouse, Mutation at the Lmx1a locus Breeding Conditions Heterozygtes qc/+ are backcorssed with F344/NSlc. Maintained in heterozygous condition. Genotyping Using markers linked with qc locus. Genotyping protocol for Lmx1a References Kuwamura, M., Muraguchi, T., Matsui, T., Ueno, M., Takenaka, S., Yamate, J., Kotani, T., Kuramoto, T., Guenet, J-L., Kitada, K., Serikawa, T. Mutation at the Lmx1a locus provokes aberrant brain development in the rat. Brain Res Dev Brain Res 155(2):99-106, 2005 Additional strain information F344 ACI