Origin
The LEXF/FXLE RI strain set has been established by Shisa et al at Saitama Cancer Center Research Institute since 1985. This RI set consists of 34 RI strains derived by reciprocal crossing of LE/Stm and F344/Stm.
Strain characteristics
The RI strains are useful genetic tool in gene mapping and analysis of complicated trait genetic diseases.
Breeding Conditions
Good breeding performance. Sib mating.
References
Shisa H, Lu L, Katoh H, Kawarai A, Tanuma J, Matsushima Y, Hiai H.
The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344.
Mamm Genome. 8(5):324-7, 1997.
Lu LM, Shisa H, Tanuma J, Hiai H.
Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis.
Br J Cancer. 80(5-6):855-61, 1999.
Voigt B, Kuramoto T, Mashimo T, Tsurumi T, Sasaki Y, Hokao R, Serikawa T.
Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic dissection of complex traits.
Physiol Genomics. 19;32(3):335-42, 2008.