| NBRP Rat No: 0009 |
Strain name: IS-Tlk/Kyo |
Commmon Name: IS/Kyo-Tlk/Kyo, IS/Kyo-Tlk, Tail anomaly Lethal Kyoto |
Rat Genome Database |
| Principal Investigator: |
Tadao Serikawa Graduate School of Medicine, Kyoto University Yoshidakonoe-cho, Sakyo-ku 606-8501 Kyoto JAPAN |
| Tel: 075-753-4360 Fax: 075-753-4409 |
Email: serikawa@anim.med.kyoto-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
 |
 |
| Coat Color |
agouti (A,B,C) |
| Inbred Generations |
F10+F55 (May 2009) |
| Usage Restrictions |
|
| Genetic Status |
|
| Comercial Availability |
|
|
| Research Category |
|
| Gene Affected |
|
| Origin |
Spontanious mutation was found in IS/Kyo inbred (F10) at Kyoto University in 1988. Tlk(Tail anomaly Lethal Kyoto) |
| Strain characteristics |
Malformations of the thoracicolumbar vertebrae leading to kyphoscoliosis with restricted spinal canals and compressed spinal cords. Mode of inheritance is unknown. |
| Breeding Conditions |
Short tail and normal rat are mated. |
| Genotyping |
|
| References |
Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157
Takano M, Ogawa E, Saitou T, Yamaguchi Y, Asano Y, Serikawa T, Kuramoto T.
Morphological features of adult rats of IS/Kyo and IS-Tlk/Kyo strains with lumbar and caudal vertebral anomalies.
Exp Anim. 2014;63(3):269-75.
Takano M, Katsumata Y, Ogawa J, Ebata T, Urasoko Y, Asano Y, Serikawa T, Kuramoto T.
Morphological features of mutant rat, IS-Tlk/Kyo, fetuses with caudal vertebral anomalies.
Congenit Anom (Kyoto). 52(1):42-47, 2012 |
| Additional strain information |
IS/Kyo |
|
|