Strain information
 NBRP Rat No: 0142  Strain name: SHR/Nig  Commmon Name: Rat Genome Database
Principal Investigator:  Mikio Nakazawa  School of Health Sciences, Faculity of Medicine, Niigata University       2-74, Asahimachi-dori, Niigata    951-8518 Niigata     Japan
Tel: 025-227-0962    Fax: 025-227-0962 Email: nakazawa@clg.niigata-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/SHR%20Nig/841a%20(Large).jpg ../images/Photos/SHR%20Nig/841z%20(Large).jpg
Coat Color  albino (c)
Inbred Generations  F70 (May 2008)
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 整形外科学
 Control Strain  Marker Strain
Gene Affected
Origin The SHR/Nig is originated in the SHR given from Prof. Okamoto at Kinki University, Japan in 1976.
Strain characteristics A substrain of SHR. Hypertension. Control strain is WKY.
Breeding Conditions Sib mating.
Genotyping
References Takeda K, Nakagawa Y, Chin WP, Imai S.
A comparison of antihypertensive effects of atenolol and propranolol in the spontaneously hypertensive, DOCA/saline hypertensive and renal hypertensive rats.
Jpn J Pharmacol. 1982 Apr;32(2):283-9.
Additional strain information SHR