Origin
The SHR/Nig is originated in the SHR given from Prof. Okamoto at Kinki University, Japan in 1976.
Strain characteristics
A substrain of SHR. Hypertension. Control strain is WKY.
References
Takeda K, Nakagawa Y, Chin WP, Imai S.
A comparison of antihypertensive effects of atenolol and propranolol in the spontaneously hypertensive, DOCA/saline hypertensive and renal hypertensive rats.
Jpn J Pharmacol. 1982 Apr;32(2):283-9.