Strain information  NBRP Rat No: 0144  Strain name: SHRSP/Ngsk  Commmon Name: SHRSP長崎 Rat Genome Database Principal Investigator:  Masami Niwa  School of Allied Medical Sciences, Nagasaki University       12-4, Sakamoto, Nagasaki    852-8523 Nagasaki     Japan Tel: 095-849-7043    Fax: 095-849-7044 Email: niwa@net.nagasaki-u.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  F?+26 (April 2012) Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others 整形外科学  Control Strain  Marker Strain Gene Affected Origin The SHRSP/Ngsk is originated in the SHRSP given from Prof. Okamoto at Kinki University, Japan in 1980. Strain characteristics SHRSP/Ngsk is little smaller than SHR/Izm in size. Age of occurrence of stroke is stable, and circulation dynamics and pathological changes are similar to those of SHRSP/Izm. The frequncy of necrosis at the epiphysis is little higher than SHRSP/Izm. Breeding Conditions Keep with normal SHRSP diet. Sib mating. Genotyping References Sakurai-Yamashita Y, Nabika T, Niwa M. Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats. Cell Mol Neurobiol. 2010 Mar;30(2):283-7. Yamashita K, Niwa M, Kataoka Y, Shigematsu K, Himeno A, Tsutsumi K, Nakano-Nakashima M, Sakurai-Yamashita Y, Shibata S, Taniyama K. Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia. J Neurochem. 1994 Sep;63(3):1042-51. Additional strain information SHR