Strain information

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NBRP Rat No: 0173

Strain name: WKY.SHRSP-(D1Smu13-D1Smu11)/Izm

Commmon Name: WKYpch1.2

Rat Genome Database

Principal Investigator:

Tohru NabikaShimane University, School of Medicine

Preservation Status:

Embryo Sperm Living Animals

Coat Color

albino (c)

Inbred Generations

F12

Usage Restrictions

The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research with the DEPOSITOR.

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

Origin

To establish this congenic strain, the QTL region was introgressed from SHRSP/Izm to WKY/Izm by repeated backcrossing following sib-mating. This congenic strain was established to cover the QTL region between D1Smu13 and D1Smu11.

Strain characteristics

Hypertension

Breeding Conditions

Good breeding performance.

Genotyping

References

Xiao B, Harada Y, Kawakami K, Nabika T.
A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress: evaluation in reciprocal congenic strains between stroke-prone spontaneously hypertensive rat and Wistar-Kyoto rat.
J Hypertens. 2011 Feb;29(2):257-65.

Additional strain information (Japanese only)

SHRSP