Strain information
NBRP Rat No: 0151
Strain name
: SDR/Slc
Commmon Name: Spontaneous Dwarf Rat
Rat Genome Database
Principal Investigator:
Representative Director Japan SLC, Inc 3371-8, Kotoh-cho, Hamamatsu 431-1103 Shizuoka Japan
Tel: 053-486-3178 Fax: 053-486-3156
Email: slc01@jslc.co.jp
Preservation Status:
Embryo
Sperm
Living Animals
Coat Color
albino (c)
Inbred Generations
F?+10
Usage Restrictions
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Gh1: growth hormone 1
Origin
In 1977, small mutant rats were discovered in a colony of Sprague Dawley rats at Morishita Pharmaceutical Co., transferred to Japan SLC, Inc.
Strain characteristics
Postnatal growth retardation. Pituitary dwarfism. Growth hormone (
Gh1
) deficiency caused by a nonsense point mutation in the Gh1 gene.
Breeding Conditions
Sib mating. Poor breeding performance.
Genotyping
References
Additional strain information
SDR