Strain information  NBRP Rat No: 0152  Strain name: HWY/Slc  Commmon Name: Hairless Wistar Yagi Rat Genome Database Principal Investigator:  Representative Director  Japan SLC, Inc       3371-8, Kotoh-cho, Hamamatsu    431-1103 Shizuoka     Japan Tel: 053-486-3178    Fax: 053-486-3156 Email: slc01@jslc.co.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino, hairless Inbred Generations  F?+11 Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Japan SLC, Inc Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin A hairless mutant rat was found in a colony of Wistar rats (Crj: Wistar), transferred to Japan SLC, Inc from Yagi Memorial Park, 1993. Strain characteristics Short pelage is sparsely distributed at weaning but, with growth, they exhibit almost complete hairlessness. Follicular cysts are seen in the dermis in 9 weeks of age. These phenotypes are due to autosomal dominant inheritance. Breeding Conditions Genotyping References Kim H, Yoshihara M, Suyama M. Comparative genomic analysis of inbred rat strains reveals the existence of ancestral polymorphisms. Mamm Genome. 2020 Apr;31(3-4):86-94. Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M. Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains. Genomics Data. 2016 Dec; 10: 155-157 Ishii Y, Tsutsui S, Doi K, Itagaki S. Hair follicles of young Wistar strain hairless rats: a histological study. J Anat. 1997 Jul;191 ( Pt 1):99-106. Additional strain information HWY