Strain information

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NBRP Rat No: 0157

Strain name: DA/Slc

Commmon Name: Dark Agouti

Rat Genome Database

Principal Investigator:

Representative DirectorJapan SLC, Inc

Preservation Status:

Embryo Sperm Living Animals

Coat Color

A,B,C

Inbred Generations

F14+48

../images/Photos/DA%20Slc/181a%20(Large).jpg

../images/Photos/DA%20Slc/181z%20(Large).jpg

Usage Restrictions

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Japan SLC, Inc

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

Origin

Kumamoto University School of Medicine> Slc (1983)

Strain characteristics

Animal model of collagen-induced arthritis (CIA), adjuvant-induced arthritis (AIA), experimental autoimmune encephalomyelitis (EAE).

Breeding Conditions

Sib mating.

Genotyping

References

Yoshimi K, Kaneko T, Voigt B, Mashimo T.
Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform.
Nat Commun. 5:4240, 2014.

Kuramoto T, Nakanishi S, Ochiai M, Nakagama H, Voigt B, Serikawa T.
Origins of Albino and Hooded Rats: Implications from Molecular Genetic Analysis across Modern Laboratory Rat Strains.
PLoS One. 2012;7(8):e43059.

Additional strain information (Japanese only)

DA rat DA/Ham