Strain information
NBRP Rat No: 0179
Strain name
: F344.Cg-
Lepr
fa
(
D7Rat16-D7Mgh20
)/Tj
Commmon Name: F.ZF/O-
lepr,Nidd1/of
Rat Genome Database
Principal Investigator:
Kozo Matsumoto The University of Tokushima Graduate School of Medicine 3-18-15 Kuramoto-cho 770-8503 Tokushima JAPAN
Tel: 088-633-9278 Fax: 088-600-9429
Email: kozo@anex.med.tokushima-u.ac.jp
Preservation Status:
Embryo
Sperm
Living Animals
Coat Color
Inbred Generations
N(5)F4
Usage Restrictions
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Origin
Established as speed congenics (5 generations, microsatellite marker) at the University of Tokushima School of Medicine, Institute for Animal Experimentation in 2002. Afterwards, maintained by sib mating.
Strain characteristics
Obesity. Show hyperglycemia in the OGTT assay.
Breeding Conditions
Good breeding performance.
Genotyping
References
Kose H, Yamada T, Matsumoto K.
Single Diabetic QTL Derived from OLETF Rat Is a Sufficient Agent for Severe Diabetic Phenotype in Combination with Leptin-Signaling Deficiency.
Exp Diabetes Res. 2012;2012:858121.Epub 2012 Dec 5.
Additional strain information