Strain information
 NBRP Rat No: 0195  Strain name: WKY/Izm  Commmon Name: Rat Genome Database
Principal Investigator:  Yukio Yamori   Disease Model Cooperative Research Association       Seisan Kaihatsukagakukenkyujyo 3F-Simogamo Morimotocho15-Sakyoku    606-0805 Kyoto     Japan
Tel: 075-744-0071    Fax: 075-744-0071 Email:
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/WKY_Izm/WKY%20Izm002%20(Large).JPG ../images/Photos/WKY_Izm/WKY%20Izm%20(Large).JPG
Coat Color  albino (c)
Inbred Generations  F110+?
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association.
They must also comply with the decisions made by the board of directors.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others SHR/Izm,SHRSP/Izmの対照系統
 Control Strain  Marker Strain
Gene Affected
Strain characteristics normotension. control strain for SHR/Izm (NBRP No.0194) and SHRSP/Izm (NBRP No.0195)
Breeding Conditions Good breeding performance.
References Yamagata K, Yamamoto M, Kawakami K, Ohara H, Nabika T.
Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats.
Neuroscience. 267:277-285, 2014.

Yamori,Y : The Spontaneously Hypertensive Rat. In: Textbook of hypertension,
ed. By Swales,J.D.,Blackwell Scientific Publication, Oxford, 1994,pp447-455
Additional strain information Wistar