Strain information  NBRP Rat No: 0195  Strain name: WKY/Izm  Commmon Name: Rat Genome Database Principal Investigator:  Yukio Yamori   Disease Model Cooperative Research Association       Seisan Kaihatsukagakukenkyujyo 3F-Simogamo Morimotocho15-Sakyoku    606-0805 Kyoto     Japan Tel: 075-744-0071    Fax: 075-744-0071 Email: dmcra@j.email.ne.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  F110+? Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association. They must also comply with the decisions made by the board of directors. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others SHR/Izm,SHRSP/Izmの対照系統  Control Strain  Marker Strain Gene Affected Origin Strain characteristics normotension. control strain for SHR/Izm (NBRP No.0194) and SHRSP/Izm (NBRP No.0195) Breeding Conditions Good breeding performance. Genotyping References Yamagata K, Yamamoto M, Kawakami K, Ohara H, Nabika T. Arginine vasopressin regulated ASCT1 expression in astrocytes from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats. Neuroscience. 267:277-285, 2014. Yamori,Y et.al. : The Spontaneously Hypertensive Rat. In: Textbook of hypertension, ed. By Swales,J.D.,Blackwell Scientific Publication, Oxford, 1994,pp447-455 Additional strain information Wistar