Strain information
 NBRP Rat No: 0204  Strain name: WKY.BUF-Pur1s/Mna  Commmon Name: Rat Genome Database
Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan
Tel: 0562-93-2486    Fax: 0562-93-4008 Email:
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  
Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin This congenic strain was established as a strain with the genetic background of WKY onto which a segment from the BUF/Mna containing the proteinuria-susceptible gene, Pur1 (on chr.13, Murayama, 1998) has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010)
Strain characteristics Mild nephrosis.
Breeding Conditions Sib mating.
References Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Kato F, Watanabe M, Matsuyama M.
Nephrotic syndrome in spontaneous thymoma rats, Buffalo/Mna.
Biomed Res 1983 4:105-9.

Murayama S, Yagyu S, Higo K, Ye C, Mizuno T, Oyabu A, Ito M, Morita H, Maeda K, Serikawa T, Matsuyama M.
A genetic locus susceptible to the overt proteinuria in BUF/Mna rat.
Mamm Genome. 1998 Nov;9(11):886-8.
Additional strain information BUF