Strain information  NBRP Rat No: 0209  Strain name: WKY.BUF-Ten2/Mna  Commmon Name: Rat Genome Database Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan Tel: 0562-93-2486    Fax: 0562-93-4008 Email: mmatsuya@fujita-hu.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations   Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin This congenic strain was established as a strain with the genetic background of WKY onto which a segment from the BUF/Mna containing the thymus enlargement, Ten2 (on chr.13, Murakumo, 1996) has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010) Strain characteristics There is no data about thymus enlargement. This congenic rat develops nephrosis in 100% of animals. Breeding Conditions Genotyping References Matsuyama M, Nagayo T Development of thymoma and myasthenia in Buffalo/Mna rats. Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977. Murakumo Y, Takahashi M, Sharma N, Arakawa A, Saito M, Amo H, Matsuyama M. Mapping of two genetic loci, Ten-1 and Ten-2, associated with thymus enlargement in BUF/Mna rats. Mamm Genome. 1996 Jul;7(7):505-8. Additional strain information WKY BUF Wistar