Strain information
 NBRP Rat No: 0211  Strain name: ACI.BUF-Ten1/Mna  Commmon Name: Rat Genome Database
Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan
Tel: 0562-93-2486    Fax: 0562-93-4008 Email:
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  agouti
Inbred Generations  
Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin This congenic strain was established as a strain with the genetic background of ACI onto which a segment from the BUF/Mna containing the thymus enlargement, Ten1 (on Chr 1, Murakumo, 1996) has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010)
Strain characteristics This congenic rat develops hyperplasia of thymus in 100% of animals.
Breeding Conditions Sib mating.
References Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Murakumo Y, Takahashi M, Sharma N, Arakawa A, Saito M, Amo H, Matsuyama M.
Mapping of two genetic loci, Ten-1 and Ten-2, associated with thymus enlargement in BUF/Mna rats.
Mamm Genome. 1996 Jul;7(7):505-8.
Additional strain information ACI BUF