Strain information
 NBRP Rat No: 0212  Strain name: ACI.BUF-Aftm1/Mna  Commmon Name: Rat Genome Database
Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan
Tel: 0562-93-2486    Fax: 0562-93-4008 Email:
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/ACI%20BUF-Aftm1_Mna/ACI BUF-Aftm1_Mna_1024.jpg
Coat Color  agouti
Inbred Generations  
Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin This congenic strain was established as a strain with the genetic background of ACI onto which a segment from the BUF/Mna containing the Aftm1 has been transferred. Please refer to NBRP No.0200 BUF/Mna. (Oct 12, 2010)
Strain characteristics This congenic rat develops muscle atrophy in 100% of animals.
Breeding Conditions Sib mating.
References Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Amo H, Saito M, Nagao S, Yagiu S, Takahashi H, Morita H, Morita TM, Matsuyama M.
Genetic regulation of slowly progressing mild muscle atrophy in fast-twitch muscles of BUF/Mna rats.
Muscle Nerve. 1997 20(10):1258-63.

松山 睦司 , 守口 匡子 , 叶 春霖 , 石川 球美子 , 松浦 晃洋
日本呼吸器外科学会雑誌 2002 16(4):7a-8a
Additional strain information ACI BUF