Strain information  NBRP Rat No: 0509  Strain name: SHR/NCrlCrlj  Commmon Name: Rat Genome Database Principal Investigator:  Shinya Takahashi  Charles river laboratories Japan       11F 3-17-16 Shinyokohama, Kouhokuku, Yokohama    222-0033 Kanagawa     Japan Tel: 045（474）9340     Fax: 045（474）9341 Email: web_order@jp.crl.com Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations   Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin This strain was established from Okamoto by selective mating of spontaneous hypertension rat from Wistar Kyoto rats in 1959. To NIH from Okamoto in 1966 at F13. To Charles River Laboratories, Inc. from NIH in 1973 at F32. To Charles River Japan, Inc. in 1980 at F51. (May 27, 2010) Strain characteristics Animal model for hypertension. The control strain is WKY. (May 27, 2010) Breeding Conditions Genotyping References Gandolgor TA, Ohara H, Cui ZH, Hirashima T, Ogawa T, Saar K, Hübner N, Watanabe T, Isomura M, Nabika T. Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/izm. Hypertension. 2013 Jul;62(1):55-61. doi: 10.1161/HYPERTENSIONAHA.111.00488. Epub 2013 May 20. Additional strain information