| NBRP Rat No: 0220 |
Strain name: RICO/Ngs |
Commmon Name: rat with increased cholesterol |
Rat Genome Database |
| Principal Investigator: |
Kazutaka Ohsawa Center for Frontier Life Sciences, Nagasaki University 1-12-4, Sakamoto, Nagasaki 852-8523 Nagasaki Japan |
| Tel: 095-819-7132 Fax: 095-819-7148 |
Email: kohsawa@net.nagasaki-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
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| Coat Color |
albino (c) |
| Inbred Generations |
F?+32 (May 2008) |
| Usage Restrictions |
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| Genetic Status |
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| Comercial Availability |
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| Research Category |
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| Gene Affected |
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| Origin |
In 1969, 2 males and 4 females with spontaneous hypercholesterolemia were selected from different colonies of albino rats. By sib-mating and selective breeding, Muller et al. established this hypercholesterolemic strain and named RICO (rats with increased cholesterol) (Muller, 1979). 1997, from Australia ARC (animal resource centre) to Nagasaki University. (Nov 6, 2009) |
| Strain characteristics |
hypercholesterolemia |
| Breeding Conditions |
Sib mating. No selective breeding. |
| Genotyping |
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| References |
Production hepatique et intestinale de cholesterol augmentee, et quantite augmentee de cholesterol circulant. MULLER et ai., 1979
Müller KR, Li JR, Dinh DM, Subbiah MT.
The characteristics and metabolism of a genetically hypercholesterolemic strain of rats (RICO).
Biochim Biophys Acta. 1979 Aug 30;574(2):334-43. |
| Additional strain information |
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