The National BioResource Project for the Rat in Japan

Strain information

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NBRP Rat No: 0221
Strain name: SHRSP.WKY-(D1Wox29-D1Arb21)/Izm
Commmon Name: SHRSPwch1.0
Principal Investigator:
Tohru NabikaShimane University, School of Medicine
Preservation Status:
Coat Color
albino (c)
Inbred Generations
F5-6
Usage Restrictions
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research with the DEPOSITOR.
Genetic Status
Comercial Availability
Research Category
Gene Affected
Origin
Strain characteristics
hypertension, stroke and disorder of the kidney
Breeding Conditions
Good breeding performance.
Genotyping
References
Xiao B, Harada Y, Kawakami K, Nabika T.
A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress: evaluation in reciprocal congenic strains between stroke-prone spontaneously hypertensive rat and Wistar-Kyoto rat.
J Hypertens. 2011 Feb;29(2):257-65.

Sakurai-Yamashita Y, Nabika T, Niwa M.
Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats.
Cell Mol Neurobiol. 2010 Mar;30(2):283-7.

Iigaya K, Kumagai H, Nabika T, Harada Y, Onimaru H, Oshima N, Takimoto C, Kamayachi T, Saruta T, Itoh H.
Relation of blood pressure quantitative trait locus on rat chromosome 1 to hyperactivity of rostral ventrolateral medulla.
Hypertension. 53(1):42-8, 2009.

Wang T, Nabika T, Notsu Y, Takabatake T.
Sympathetic regulation of the renal functions in rats reciprocally congenic for chromosome 1 blood pressure quantitative trait locus.
Hypertens Res. 31(3):561-8, 2008.
Additional strain information (Japanese only)