Strain information  NBRP Rat No: 0280  Strain name: DA-Tg(CAG-lacZ)30Jmsk  Commmon Name: LacZ30 Rat Genome Database Principal Investigator:  Eiji Kobayashi  Center for Molecular Medicine, Jichi Medical School       3311-1, Yakushiji, Shimono-shi, Tochigi    329-0498 Tochigi     Japan Tel: 0285-58-7446    Fax: 0285-44-5365 Email: eijikoba@jichi.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color   Inbred Generations   Usage Restrictions  The recipient is requested to cite in the following literature designated by the DEPOSITOR. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected lacZ: beta-galactosidase, E. coli Origin This strain was established at Jichi Medical School. Strain characteristics This transgenic strain expresses LacZ gene ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscle. The strain NBRP No.0280 (line30) is more strongly stained by X-gal staining. Breeding Conditions Good breeding performance. Genotyping References Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E. Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardium. Biochem Biophys Res Commun. 2003 Jun 13;305(4):904-8. Takahashi M, Hakamata Y, Takeuchi K, Kobayashi E. Effects of different fixatives on beta-galactosidase activity. J Histochem Cytochem. 2003 Apr;51(4):553-4. Additional strain information DA