Strain information
 NBRP Rat No: 0280  Strain name: DA-Tg(CAG-lacZ)30Jmsk  Commmon Name: LacZ30 Rat Genome Database
Principal Investigator:  Eiji Kobayashi  Center for Molecular Medicine, Jichi Medical School       3311-1, Yakushiji, Shimono-shi, Tochigi    329-0498 Tochigi     Japan
Tel: 0285-58-7446    Fax: 0285-44-5365 Email:
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  
Inbred Generations  
Usage Restrictions  The recipient is requested to cite in the following literature designated by the DEPOSITOR.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected lacZ: beta-galactosidase, E. coli
Origin This strain was established at Jichi Medical School.
Strain characteristics This transgenic strain expresses LacZ gene ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscle. The strain NBRP No.0280 (line30) is more strongly stained by X-gal staining.
Breeding Conditions Good breeding performance.
References Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E.
Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardium.
Biochem Biophys Res Commun. 2003 Jun 13;305(4):904-8.

Takahashi M, Hakamata Y, Takeuchi K, Kobayashi E.
Effects of different fixatives on beta-galactosidase activity.
J Histochem Cytochem. 2003 Apr;51(4):553-4.
Additional strain information DA