Strain information

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NBRP Rat No:

Strain name: W-Tg(CAG-DsRed2/GFP)1Jmsk

Commmon Name: Wistar-Tg(CAG-DsRed2/GFP)1Jmsk, Wistar-Tg(CAG-LRL,GFP)1Jmsk, LRL-GFP1

Rat Genome Database

Principal Investigator:

Eiji KobayashiCenter for Molecular Medicine, Jichi Medical School

Preservation Status:

Embryo Sperm Living Animals

Coat Color

albino (c)

Inbred Generations

Usage Restrictions

The recipient of BIOLOGICAL RESOUCE shall obtain a prior written consent on use of it from the DEPOSITOR for one year from the deposited date forth. After that, the recipient is requested to cite in the following literature designated by the DEPOSITOR.

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

DsRed: red fluorescent protein, GFP: Green Fluorescent Protein, jellyfish

Origin

This strain was established at Jichi Medical School. This transgenic rat was originated from Crlj:WI.

Strain characteristics

DsRed2/GFP double-reporter transgenic rat driven under a ubiquitous CAG promoter. In this system, DsRed2 expression was replaced with GFP expression after Cre recombinase-mediated excision.

Breeding Conditions

Good breeding performance.

Genotyping

References

* Sato Y, Endo H, Ajiki T, Hakamata Y, Okada T, Murakami T, Kobayashi E.
Establishment of Cre/LoxP recombination system in transgenic rats.
Biochem Biophys Res Commun. 9;319(4):1197-202, 2004.

Additional strain information (Japanese only)

Wistar