| NBRP Rat No: |
Strain name: W-Tg(CAG-DsRed2/GFP)15Jmsk |
Commmon Name: Wistar-Tg(CAG-DsRed2/GFP)15Jmsk, Wistar-Tg(CAG-LRL,GFP)15Jmsk, LRL-GFP15 |
Rat Genome Database |
| Principal Investigator: |
Eiji Kobayashi Center for Molecular Medicine, Jichi Medical School 3311-1, Yakushiji, Shimono-shi, Tochigi 329-0498 Tochigi Japan |
| Tel: 0285-58-7446 Fax: 0285-44-5365 |
Email: eijikoba@jichi.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
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| Coat Color |
albino (c) |
| Inbred Generations |
F6 (Jun 2010) |
| Usage Restrictions |
The recipient of BIOLOGICAL RESOUCE shall obtain a prior written consent on use of it from the DEPOSITOR for one year from the deposited date forth. After that, the recipient is requested to cite in the following literature designated by the DEPOSITOR. |
| Genetic Status |
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| Comercial Availability |
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| Research Category |
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| Gene Affected |
DsRed: red fluorescent protein, GFP: Green Fluorescent Protein, jellyfish |
| Origin |
This strain was established at Jichi Medical School. This transgenic rat was originated from Crlj:WI. |
| Strain characteristics |
DsRed2/GFP double-reporter transgenic rat driven under a ubiquitous CAG promoter.
In this system, DsRed2 expression was replaced with GFP expression after Cre recombinase-mediated excision. |
| Breeding Conditions |
Good breeding performance. |
| Genotyping |
Genotyping protocol for pDsRed2
Genotyping protocol for LoxP site |
| References |
Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO.
A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits.
Front Neurosci. 2015; 9: 487.
* Sato Y, Endo H, Ajiki T, Hakamata Y, Okada T, Murakami T, Kobayashi E.
Establishment of Cre/LoxP recombination system in transgenic rats.
Biochem Biophys Res Commun. 9;319(4):1197-202, 2004. |
| Additional strain information |
Wistar |
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