Strain information  NBRP Rat No: 0283  Strain name: W-Tg(CAG-cre)81Jmsk  Commmon Name: Wistar-Tg(CAG-cre)81Jmsk, Wistar-Tg(CAG-NCre)81Jmsk, NCre81 Rat Genome Database Principal Investigator:  Eiji Kobayashi  Center for Molecular Medicine, Jichi Medical School       3311-1, Yakushiji, Shimono-shi, Tochigi    329-0498 Tochigi     Japan Tel: 0285-58-7446    Fax: 0285-44-5365 Email: eijikoba@jichi.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  F?+21 (March 2012) Usage Restrictions  The recipient is requested to cite in the following literature designated by the DEPOSITOR. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin This strain was established at Jichi Medical School. Strain characteristics This strain expresses the Cre recombinase ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscles. Transgene was integrated into the Chr X. Breeding Conditions Good breeding performance. Genotyping Genotyping protocol for CAG Promoter Genotyping protocol for Cre References Fukamachi K, Tanaka H, Sakai Y, Alexander DB, Futakuchi M, Tsuda H, Suzui M. A novel reporter rat strain that expresses LacZ upon Cre‐mediated recombination. Genesis. 2013 Apr;51(4):268-74. Sato Y, Endo H, Ajiki T, Hakamata Y, Okada T, Murakami T, Kobayashi E. Establishment of Cre/LoxP recombination system in transgenic rats. Biochem Biophys Res Commun. 9;319(4):1197-202, 2004. Additional strain information Wistar