Usage Restrictions
The recipient is requested to cite in the following literature designated by the DEPOSITOR.
Origin
This strain was established at Jichi Medical School.
Strain characteristics
This strain expresses the Cre recombinase ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscles. Transgene was integrated into the Chr X.
Breeding Conditions
Good breeding performance.
References
Haijima A, Imai H, Matsushita N, Morita K, Kobayashi K, Ishida S, Iida R, Mashimo T, Asano M.
Functional behavioral profiling of multiple cre-driver rat lines.
Exp Anim. 2026 Jan 9. doi: 10.1538/expanim.25-0115.
Uchimura Y, Hino K, Hattori K, Kubo Y, Owada A, Kimura T, Sugawara L, Kume S, Bellier JP, Yanagisawa D, Shiino A, Nakayama T, Daigo Y, Mashimo T, Udagawa J.
Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume.
PLoS One. 2024 Aug 28;19(8):e0309461.
Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T.
CLICK: one-step generation of conditional knockout mice.
BMC Genomics. 2018 May 2;19(1):318.
Fukamachi K, Tanaka H, Sakai Y, Alexander DB, Futakuchi M, Tsuda H, Suzui M.
A novel reporter rat strain that expresses LacZ upon Cre‐mediated recombination.
Genesis. 2013 Apr;51(4):268-74.
Sato Y, Endo H, Ajiki T, Hakamata Y, Okada T, Murakami T, Kobayashi E.
Establishment of Cre/LoxP recombination system in transgenic rats.
Biochem Biophys Res Commun. 9;319(4):1197-202, 2004.