| NBRP Rat No: 0354 |
Strain name: TM.KDP-Cblb/Nyo |
Commmon Name: TM.KDP-Cblb, TM.KDP-Cblb congenic |
Rat Genome Database |
| Principal Investigator: |
Susumu Seino Kobe University Graduate School of Medicine 7-5-1 Kusunoki-cho, Chuou-Ku, Kobe 650-0017 Hyogo Japan |
| Tel: 078-382-5364 Fax: 078-382-5379 |
Email: seino@med.kobe-u.ac.jp, yokoi@med.kobe-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
![]() |
![]() |
| Coat Color |
a,B,C,h,P,r |
| Inbred Generations |
N7F8 |
| Usage Restrictions |
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.The recipients shall cite the references of the resource and acknowledge the developer as the source of the resource in the publications. Depending on the project of the recipients, a collaborative arrangement with the developer could be required. In this case, the recipients shall discuss with the developer. |
| Genetic Status |
|
| Comercial Availability |
|
|
| Research Category |
|
| Gene Affected |
Cblb: Casitas B-lineage lymphoma b |
| Origin |
|
| Strain characteristics |
insulitis |
| Breeding Conditions |
Homozygous Cblb rats are usually infertile in both sexes and are therefore maintained by crossing heterozygous individuals (segregating inbred strain). |
| Genotyping |
|
| References |
Yokoi N, Komeda K, Wang HY, Yano H, Kitada K, Saitoh Y, Seino Y, Yasuda K, Serikawa T, Seino S.
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
Nat Genet. 31(4):391-4, 2002
Yokoi N, Namae M, Fuse M, Wang HY, Hirata T, Seino S, Komeda K.
Establishment and characterization of the Komeda diabetes-prone rat as a segregating inbred strain.
Exp Anim. 52(4):295-301, 2003 |
| Additional strain information |
|
|
|