Strain information
 NBRP Rat No: 0355  Strain name: ACI.F344-(D16Rat17-D16Rat15)/Nkg  Commmon Name: ACI.F344-(D16Rat17-D16Rat15) Rat Genome Database
Principal Investigator:  Hitoshi Nakagama  National Cancer center        5-1-1 Tsukiji, Chuo-ku    104-0045 Tokyo     Japan
Tel: 03-3542-2511    Fax: 03-3542-2530 Email: hnakagam@ncc.go.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  A,B,C,H
Inbred Generations  N8F12
Usage Restrictions   In publishing, an acknowledgment to the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin F344 rats are susceptible and ACI rats are resistant to PhIP(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)-induced ACF formation (Nagao, 1998). Targeting on susceptible gene for colon tumor on rat chromosome 16 (Nakagama, 1999), this congenic strain was established by backcrossing F344/Jcl, as a donor strain, and ACI/NJcl, as a recipient strain. (Jul 7, 2009)
Strain characteristics This congenic strain has almost the same characterization as shown in ACI/N. (Jul 7, 2009)
Breeding Conditions Good breeding performance.
Genotyping
References
Additional strain information