Strain information
 NBRP Rat No: 0300  Strain name: LEW-Tg(Gt(ROSA)26Sor-luc)21Jmsk  Commmon Name: LEW-Tg(Rosa-luc)21Jmsk, Luc21 Rat Genome Database
Principal Investigator:  Eiji Kobayashi  Center for Molecular Medicine, Jichi Medical School       3311-1, Yakushiji, Shimono-shi, Tochigi    329-0498 Tochigi     Japan
Tel: 0285-58-7446    Fax: 0285-44-5365 Email: eijikoba@jichi.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  
Usage Restrictions  In publishing, the references designated by the DEPOSITOR are requested to be cited.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected luc: luciferase, firefly
Origin This strain was established at Jichi Medical School. This transgenic rat was originated from LEW (RT1l) strain purchased from Charles River Japan.
Strain characteristics This strain expresses luciferase ubiquitously driven by the gene trap ROSA 26 promoter. The strength of the transgene expression of this strain is poorer than that of luc11 (NBRP No.0299). The expression of transgene is ubiquitous except for bone-marrow cell and blood.
Breeding Conditions Good breeding performance.
Genotyping
References Hata T, Uemoto S, Fujimoto Y, Murakami T, Tateno C, Yoshizato K, Kobayashi E.
Transplantation of Engineered Chimeric Liver With Autologous Hepatocytes and Xenobiotic Scaffold.
Ann Surg. 2013 Mar;257(3):542-7.

Hata T, Iwasaki J, Hishikawa S, Fujimoto Y, Uemoto S, Kobayashi E.
Development of a portocaval shunt using a small intestinal segment in rats.
Microsurgery. 2010 May;30(4):302-6.

Iwasaki J, Hata T, Hishikawa S, Fujimoto Y, Uemoto S, Murakami T, Kobayashi E.
Use of rat segmental intestine for fetal pancreatic transplantation.
Microsurgery. 2010 May;30(4):296-301.

Hakamata Y, Murakami T, Kobayashi E.
"Firefly rats" as an organ/cellular source for long-term in vivo bioluminescent imaging.
Transplantation. 27;81(8):1179-84, 2006.
Additional strain information LEW