Strain information
 NBRP Rat No: 0371  Strain name: W-Tg(S100b-EGFP)Scell  Commmon Name: Wistar-Tg(S100b-EGFP)Scell, Wistar-Tg(S100b-GFP)Scell, s100b-GFP Rat Genome Database
Principal Investigator:  Kinji Inoue  Faculty of Science, Saitama University       255 Shimo-ohkubo Sakura-ku Saitama    338-8570 Saitama     Japan
Tel: 048‐858-3422    Fax: 048‐858-3422 Email: kininoue@mail.saitama-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photo/Wistar-Tg_S100b-GFP_Scell/Wistar-Tg_S100b-GFP_Scell_1024.jpg
Coat Color  albino (c)
Inbred Generations  F?+8 (April 2012)
Usage Restrictions   In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing, an acknowledgment to the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected S100b, GFP: Green Fluorescent Protein, jellyfish
Origin
Strain characteristics This transgenic rats expressed GFP in FS cells specifically in the anterior lobe. GFP is also expressed in other known S-100β expressing cells, i.e., brain astrocytes, adipocytes and chondrocytes.
Breeding Conditions Transgene dose not affect their breeding.
Genotyping Genotyping protocol for S100β-EGFP
References Syaidah R, Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kikuchi M, Yashiro T.
Fibromodulin Expression in Folliculostellate Cells and Pericytes Is Promoted by TGFβ Signaling in Rat Anterior Pituitary Gland.
Acta Histochem Cytochem.2016 Dec 28; 49 (6): 171–179.

Patterson KC, Hawkins VE, Arps KM, Mulkey DK, Olsen ML.
MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats.
Hum Mol Genet. 2016 Aug 1;25(15):3303-3320.

Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K.
Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes.
Endocrinology. 2007 Apr;148(4):1518-23.
Additional strain information