Strain information  NBRP Rat No: 0371  Strain name: W-Tg(S100b-EGFP)Scell  Commmon Name: Wistar-Tg(S100b-EGFP)Scell, Wistar-Tg(S100b-GFP)Scell, s100b-GFP Rat Genome Database Principal Investigator:  Kinji Inoue  Faculty of Science, Saitama University       255 Shimo-ohkubo Sakura-ku Saitama    338-8570 Saitama     Japan Tel: 048‐858-3422    Fax: 048‐858-3422 Email: kininoue@mail.saitama-u.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  F?+8 (April 2012) Usage Restrictions   In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing, an acknowledgment to the DEPOSITOR is requested. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected S100b, GFP: Green Fluorescent Protein, jellyfish Origin Strain characteristics This transgenic rats expressed GFP in FS cells specifically in the anterior lobe. GFP is also expressed in other known S-100β expressing cells, i.e., brain astrocytes, adipocytes and chondrocytes. Breeding Conditions Homozygous rats have difficulty in breeding. Mating between heterozygous and wild-type rats. Genotyping Genotyping protocol for S100β-EGFP References Gallucci A, Patterson KC, Weit AR, Van Der Pol WJ, Dubois LG, Percy AK, Morrow CD, Campbell SL, Olsen ML. Microbial community changes in a female rat model of Rett syndrome. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13:109:110259. Syaidah R, Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kikuchi M, Yashiro T. Fibromodulin Expression in Folliculostellate Cells and Pericytes Is Promoted by TGFβ Signaling in Rat Anterior Pituitary Gland. Acta Histochem Cytochem.2016 Dec 28; 49 (6): 171–179. Patterson KC, Hawkins VE, Arps KM, Mulkey DK, Olsen ML. MeCP2 Deficiency Results in Robust Rett-like Behavioral and Motor Deficits in Male and Female Rats. Hum Mol Genet. 2016 Aug 1;25(15):3303-3320. Itakura E, Odaira K, Yokoyama K, Osuna M, Hara T, Inoue K. Generation of transgenic rats expressing green fluorescent protein in S-100beta-producing pituitary folliculo-stellate cells and brain astrocytes. Endocrinology. 2007 Apr;148(4):1518-23. Additional strain information