Strain information
 NBRP Rat No: 0044  Strain name: NIG-III/Hok  Commmon Name: NIG-III Rat Genome Database
Principal Investigator:  Kazuhiro Kitada  Creative Research Initiative "Sousei", Hokkaido University       Kita 10 Nishi 8, Kita-ku    060-0810 Hokkaido     JAPAN
Tel: 011-706-3582    Fax: 011-726-3476 Email:
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/NIG_III/1731a1024.jpg ../images/Photos/NIG_III/1731z1024.jpg
Coat Color  yellow agouti (a,B,C,H,p<sup>m</sup>)
Inbred Generations  F33+84+23 (April 2012)
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
For a commercial use of this resource, a new contract must be concluded between the depositor and the recipient.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin National Institute of Genetics(Ms)→Hokkaido University, Cancer 1975 F32→Hokkaido University, Laboratory of Experimental Animal Science(Hok) 1975, F33→Hokkaido University, Center for Experimental Plants & Animals(Hok) 1982, F53
Strain characteristics From a mating in 1956 between a wild rat trapped in Misima, Japan, and Castle's black rat. pink-eyed dilution (p) mutation.
Breeding Conditions Good breeding performance. Sib-mating.
References Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157

Igarashi M, Hippo Y, Ochiai M, Fukuda H, Nakagama H.
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Biochem Biophys Res Commun. 2013 Dec 13. pii: S0006-291X(13)02128-1.

Kuramoto T, Gohma H, Kimura K, Wedekind D, Hedrich HJ, Serikawa T.
The rat pink-eyed dilution (p) mutation: an identical intragenic deletion in pink-eye dilute-coat strains and several Wistar-derived albino strains.
Mamm Genome. 16(9):712-9, 2005.
Additional strain information NIG