Strain information
 NBRP Rat No: 0454  Strain name: SHRSP/5Dmcr  Commmon Name: SHRSP5/Dmcr, SHRALR/Izm, ALR (arteriolipidosis-prone rats), SHRAP (arteriolipidosis-prone SHR) Rat Genome Database
Principal Investigator:  Yukio Yamori   Disease Model Cooperative Research Association       Seisan Kaihatsukagakukenkyujyo 3F-Simogamo Morimotocho15-Sakyoku    606-0805 Kyoto     Japan
Tel: 075-744-0071    Fax: 075-744-0071 Email: dmcra@j.email.ne.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  F31
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The users must join a disease model cooperative research association, and obey various regulations stipulated in the rules of the association. They must also comply with the decisions made by the board of directors.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin
Strain characteristics Hypertension, cardiomegaly, nephrosclerosis
Breeding Conditions
Genotyping
References Moriya T, Kitamori K, Naito H, Yanagiba Y, Ito Y, Yamagishi N, Tamada H, Jia X, Tsuchikura S, Ikeda K, Yamori Y, Nakajima T.
Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat.
Environ Health Prev Med. 2012 Nov;17(6):444-56.

Kitamori K, Naito H, Tamada H, Kobayashi M, Miyazawa D, Yasui Y, Sonoda K, Tsuchikura S, Yasui N, Ikeda K, Moriya T, Yamori Y, Nakajima T.
Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr.
Environ Health Prev Med. 2012 May;17(3):173-82.
Additional strain information