Strain information  NBRP Rat No: 0437  Strain name: FOK/Ncu  Commmon Name: 古山ラット Rat Genome Database Principal Investigator:  Fujiya Furuyama  Nagoya City University Graduate School of Medical Sciences       1 Kawasumi, Mizuho-ku, Nagoya    467-8601 Aichi     Japan Tel: 052 853-8136    Fax: 052-842-3069 Email: heiza-ff@med.nagoya-cu.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  albino (c) Inbred Generations  F63+2 (May 2008) Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. Use of BIOLOGICAL RESOURCE shall be limited to collaborative researches with the DEPOSITOR. Detail of roles shall be discussed prior to start of the research. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others 環境適応（統合生理学）  Control Strain  Marker Strain Gene Affected Origin Rat resistant to an ambient temperature of 42.5℃ were selected, inbred for more than 30 generations, and designated FOK (Furuyama, 1993). Wistar/MK, Jcl:Wistar, Wistar/MS, HOS:Wistar and Std:Wistar were used at first. (Mar 30, 2010) Strain characteristics FOK shows heat tolerance (Furuyama, 1993) and cold tolerance (Yahata, 1999). (Mar 30, 2010) Breeding Conditions Genotyping References Furuyama F, Ohara K. Genetic development of an inbred rat strain with increased resistance adaptation to a hot environment. Am J Physiol. 265(4 Pt 2):R957-62, 1993. Shido O, Sakurada S, Sugimoto N, Furuyama F, Nagasaka T. Thermoeffector thresholds and preferred ambient temperatures of the FOK rat. Am J Physiol. 274(3 Pt 2):R604-9, 1998. Additional strain information