Strain information  NBRP Rat No: 0050  Strain name: LEA/Tj  Commmon Name: Rat Genome Database Principal Investigator:  Kozo Matsumoto  The University of Tokushima Graduate School of Medicine       3-18-15 Kuramoto-cho    770-8503 Tokushima     JAPAN Tel: 088-633-9278    Fax: 088-600-9429 Email: kozo@anex.med.tokushima-u.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color   Inbred Generations  F47+53 Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected Origin Found in Long Evans strain at Kobe University > Inbreeding at Hokkaido University > Otsuka Pharmaceutical Co. > The University of Tokushima 1989 Strain characteristics Breeding Conditions Good breeding performance. Sib mating. Genotyping References Shimizu Y, Yanobu-Takanashi R, Nakano K, Hamase K, Shimizu T, Okamura T. A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats. Mamm Genome. 2019 Feb;30(1-2):23-33. Nakajima M, Kato J, Kohgo Y, Takeichi N, Niitsu T. Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. Alcohol Alcohol 29 Suppl 1:39-43, 1994 Additional strain information LEA