Strain information

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NBRP Rat No: 0050

Strain name: LEA/Tj

Commmon Name:

Rat Genome Database

Principal Investigator:

Kozo MatsumotoThe University of Tokushima Graduate School of Medicine

Preservation Status:

Embryo Sperm Living Animals

Coat Color

Inbred Generations

F47+53

Usage Restrictions

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

Origin

Found in Long Evans strain at Kobe University > Inbreeding at Hokkaido University > Otsuka Pharmaceutical Co. > The University of Tokushima 1989

Strain characteristics

Breeding Conditions

Good breeding performance. Sib mating.

Genotyping

References

Shimizu Y, Yanobu-Takanashi R, Nakano K, Hamase K, Shimizu T, Okamura T.
A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats.
Mamm Genome. 2019 Feb;30(1-2):23-33.

Nakajima M, Kato J, Kohgo Y, Takeichi N, Niitsu T. Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. Alcohol Alcohol 29 Suppl 1:39-43, 1994

Additional strain information (Japanese only)

LEA