Strain information
 NBRP Rat No: 0485  Strain name: SR/JrNgs  Commmon Name: Dhal SR Rat Rat Genome Database
Principal Investigator:  Kazutaka Ohsawa  Center for Frontier Life Sciences, Nagasaki University       1-12-4, Sakamoto, Nagasaki    852-8523 Nagasaki     Japan
Tel: 095-819-7132    Fax: 095-819-7148 Email: kohsawa@net.nagasaki-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  F?+71 (May 2009)
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin DahlSR/JrNgs rat derived from Dr. Rapp JP of Department of Physiology, Medical University of Ohio to Nagasaki Univ. in 1986.
Strain characteristics Resistance to the hypertensive effect of a high salt (NaCl) diet. Control strain for SS/JrNgs (NBRP No.0484).
Breeding Conditions Sib mating.
Genotyping
References Baba K, Mulrow PJ, Franco-Saenz R, and Rapp JP.
Suppression of Adrenal Renin in Dahl Salt-Sensitive Rats.
Hypertension 8:1149-1153, 1986.

Kusano E, Baba K, Rapp JP, Franco-Saenz R, and Mulrow PJ.
Adrenal Renin in Dahl Salt-Sensitive Rats: A Genetic Study.
J Hypertension 4 (suppl 5):S20-S22, 1986.

Kawai K, Baba K, Senba M, Nakamura T, Doi Y, yamaguchi T, Hashiba K and Tsuchiyama H
Effect of the adrenal inhibitor trilostane on the morphology of the adrenocortical cells of Dahl salt-sensitive and Dahl salt-resistant rats.
Int J Exp Path 72:456-462, 1991.

Ferdaus MZ, Xiao B, Ohara H, Nemoto K, Harada Y, Saar K, Hübner N, Isomura M, Nabika T.
Identification of stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
PLoS One. 9(4):e95091, 2014.
Additional strain information