NBRP Rat No: 0485 |
Strain name: SR/JrNgs |
Commmon Name: Dhal SR Rat |
Rat Genome Database |
Principal Investigator: |
Kazutaka Ohsawa Center for Frontier Life Sciences, Nagasaki University 1-12-4, Sakamoto, Nagasaki 852-8523 Nagasaki Japan |
Tel: 095-819-7132 Fax: 095-819-7148 |
Email: kohsawa@net.nagasaki-u.ac.jp |
Preservation Status: |
Embryo Sperm Living Animals |
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Coat Color |
albino (c) |
Inbred Generations |
F?+71 (May 2009) |
Usage Restrictions |
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Genetic Status |
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Comercial Availability |
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Research Category |
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Gene Affected |
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Origin |
DahlSR/JrNgs rat derived from Dr. Rapp JP of Department of Physiology, Medical University of Ohio to Nagasaki Univ. in 1986. |
Strain characteristics |
Resistance to the hypertensive effect of a high salt (NaCl) diet. Control strain for SS/JrNgs (NBRP No.0484). |
Breeding Conditions |
Sib mating. |
Genotyping |
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References |
Baba K, Mulrow PJ, Franco-Saenz R, and Rapp JP.
Suppression of Adrenal Renin in Dahl Salt-Sensitive Rats.
Hypertension 8:1149-1153, 1986.
Kusano E, Baba K, Rapp JP, Franco-Saenz R, and Mulrow PJ.
Adrenal Renin in Dahl Salt-Sensitive Rats: A Genetic Study.
J Hypertension 4 (suppl 5):S20-S22, 1986.
Kawai K, Baba K, Senba M, Nakamura T, Doi Y, yamaguchi T, Hashiba K and Tsuchiyama H
Effect of the adrenal inhibitor trilostane on the morphology of the adrenocortical cells of Dahl salt-sensitive and Dahl salt-resistant rats.
Int J Exp Path 72:456-462, 1991.
Ferdaus MZ, Xiao B, Ohara H, Nemoto K, Harada Y, Saar K, Hübner N, Isomura M, Nabika T.
Identification of stim1 as a candidate gene for exaggerated sympathetic response to stress in the stroke-prone spontaneously hypertensive rat.
PLoS One. 9(4):e95091, 2014. |
Additional strain information |
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