| NBRP Rat No: 0051 |
Strain name: LEC/Tj |
Commmon Name: |
Rat Genome Database |
| Principal Investigator: |
Kozo Matsumoto The University of Tokushima Graduate School of Medicine 3-18-15 Kuramoto-cho 770-8503 Tokushima JAPAN |
| Tel: 088-633-9278 Fax: 088-600-9429 |
Email: kozo@anex.med.tokushima-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
 |
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| Coat Color |
cinnamon-like (A,B,C,D,r) |
| Inbred Generations |
F45+55 |
| Usage Restrictions |
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| Genetic Status |
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| Comercial Availability |
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| Research Category |
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| Gene Affected |
Atp7b: ATPase, Cu++ transporting, beta polypeptide, Ptprk: protein tyrosine phosphatase, receptor type, K |
| Origin |
Found in Long Evans strain at Kobe University > Inbreeding at Hokkaido University > Otsuka Pharmaceutical Co. > The University of Tokushima 1989 |
| Strain characteristics |
Hepatitis, jaundice, and a defect of T cell maturation. |
| Breeding Conditions |
Good breeding performance. Sib mating. |
| Genotyping |
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| References |
Nakajima M, Kato J, Kohgo Y, Takeichi N, Niitsu T. Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. Alcohol Alcohol 29 Suppl 1:39-43, 1994
Kose H, Sakai T, Tsukumo S, Wei K, Yamada T, Yasutomo K, Matsumoto K.
Maturational arrest of thymocyte development is caused by a deletion in the receptor-like protein tyrosine phosphatase kappa gene in LEC rats.
Genomics. 2007 Jun;89(6):673-7.
Yoshihara M, Sato T, Saito D, Ohara O, Kuramoto T, Suyama M.
Application of target capture sequencing of exons and conserved non-coding sequences to 20 inbred rat strains.
Genomics Data. 2016 Dec; 10: 155-157 |
| Additional strain information |
LEC |
|