Strain information
 NBRP Rat No: 0533  Strain name: BN.LEC-(D4Rat128-D4Rat238)/Hkv  Commmon Name: B1 Rat Genome Database
Principal Investigator:  Takashi Agui  Graduate School of Veterinary Medicine       Nishi 9 Kita 18 jou Kita-ku, Sapporo    060-0818 Hokkaido     Japan
Tel: 011-706-5106     Fax: 011-706-5106 Email: agui@vetmed.hokudai.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  non-agouti brown
Inbred Generations  N6F13
Usage Restrictions  An article is in progress. Users should be required an approval form from dipositor.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 放射線高感受性
 Control Strain  Marker Strain
Gene Affected
Origin The genetic region between D4Rat128 and D4Rat106 of LEC/Ncu was introgressed to BN/Ncu using “speed congenic” method to establish the congenic strain. One QTL which showed very strong linkage to the X-ray hypersensitivity of LEC rats was mapped on chromosome 4 (Agui, 2000). (Jul 15, 2010)
Strain characteristics The congenic rats partially have the X-ray sensitivity of LEC rats. (Jul 15, 2010)
Breeding Conditions Sib mating.
Genotyping
References Agui T, Miyamoto T, Jung CG, Tsumagari T, Masuda K, Manabe T.
Genetic linkage analysis of X-ray hypersensitivity in the LEC mutant rat.
Mamm Genome. 11(10):862-5, 2000.
Additional strain information