Strain information
NBRP Rat No: 0532
Strain name
: BN.LEC-(
D4Rat78-D4Rat238
)/Hkv
Commmon Name: B2
Rat Genome Database
Principal Investigator:
Takashi Agui Graduate School of Veterinary Medicine Nishi 9 Kita 18 jou Kita-ku, Sapporo 060-0818 Hokkaido Japan
Tel: 011-706-5106 Fax: 011-706-5106
Email: agui@vetmed.hokudai.ac.jp
Preservation Status:
Embryo
Sperm
Living Animals
Coat Color
non-agouti brown
Inbred Generations
N6F14
Usage Restrictions
An article is in progress. Users should be required an approval form from dipositor.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others 放射線高感受性
Control Strain
Marker Strain
Gene Affected
Origin
The genetic region between D4Rat78 and D4Rat238 of LEC/Ncu was introgressed to BN/Ncu using “speed congenic” method to establish the congenic strain. One QTL which showed very strong linkage to the X-ray hypersensitivity of LEC rats was mapped on chromosome 4 (Agui, 2000). (Jul 2, 2015)
Strain characteristics
The congenic rats partially have the X-ray sensitivity of LEC rats.
Breeding Conditions
Sib mating.
Genotyping
References
Agui T, Miyamoto T, Jung CG, Tsumagari T, Masuda K, Manabe T.
Genetic linkage analysis of X-ray hypersensitivity in the LEC mutant rat.
Mamm Genome. 11(10):862-5, 2000.
Additional strain information