| NBRP Rat No: 0570 |
Strain name: KFRS3A/Kyo |
Commmon Name: SRR03-mink,Pearl |
Rat Genome Database |
| Principal Investigator: |
Takashi Kuramoto Graduate School of Medicine, Kyoto University Yoshidakonoe-cho, Sakyo-ku 606-8501 Kyoto Japan |
| Tel: 075-753-4494 Fax: 075-753-4409 |
Email: kuramot@anim.med.kyoto-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
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| Coat Color |
mink, Pearl |
| Inbred Generations |
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| Usage Restrictions |
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
For a commercial use of this resource, a new contract must be concluded between the depositor and the recipient. |
| Genetic Status |
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| Comercial Availability |
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| Research Category |
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| Gene Affected |
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| Origin |
One male rat "SRR-Rocket Science" was introduced from American fancy rat colony (Spoiled Ratten Rattery: SRR, in Kansas City, Missouri) to Kyoto University on July 13, 2005. Inbreeding started from F1 progeny of male "SRR-Rocket Science" and a female PVG/Seac. Homozygous rats for mink were selected for inbreeding. (Sep 25, 2009) |
| Strain characteristics |
This strain has two mutations, American mink (am) which causes light brown body hair and Pearl (Pel) which causes lighter coat color and is lethal in the embryonic period if homozygous. Genetic analyses mapped am to Chr 1 (Kuramoto, 2010). A SINE insertion was identified in the exon 7 of Hermansky-Pudlak syndrome 5 (Hps5)gene (Kuramoto, 2010). (Jul 4, 2011) |
| Breeding Conditions |
Maintained by crossing of heterozygous and wild-type for Pearl mutation. This strain is heterozygous for Pearl mutation (segregating strain) and homozygous for mink mutation. Good breeding performance. (Sep 25, 2009) |
| Genotyping |
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| References |
Kuramoto T, Yokoe M, Yagasaki K, Kawaguchi T, Kumafuji K, Serikawa T.
Genetic analyses of fancy rat-derived mutations.
Exp Anim. 2010;59(2):147-55.
Takashi Kuramoto, Satoshi Nakanishi, Ken-ichi Yamasaki, Kenta Kumafuji, Yuichi Sakakibara, Yuki Neoda, Akiko Takizawa, Takehito Kaneko, Mito Otsuki, Ryoko Hashimoto, Birger Voigt, Tomoji Mashimo and Tadao Serikawa
Genetic Quality Control of the Rat Strains at the National Bio Resource Project-Rat.
ibc.2010 Volume 2 Article no. 0012
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| Additional strain information |
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