Strain information
 NBRP Rat No: 0570  Strain name: KFRS3A/Kyo  Commmon Name: SRR03-mink,Pearl Rat Genome Database
Principal Investigator:  Takashi Kuramoto  Graduate School of Medicine, Kyoto University       Yoshidakonoe-cho, Sakyo-ku    606-8501 Kyoto     Japan
Tel: 075-753-4494    Fax: 075-753-4409 Email:
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/KFRS3A_Kyo_mink_pearl/2231-1a.JPG ../images/Photos/KFRS3A_Kyo_mink_pearl/2231a.JPG
Coat Color  mink, Pearl
Inbred Generations  
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
For a commercial use of this resource, a new contract must be concluded between the depositor and the recipient.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin One male rat "SRR-Rocket Science" was introduced from American fancy rat colony (Spoiled Ratten Rattery: SRR, in Kansas City, Missouri) to Kyoto University on July 13, 2005. Inbreeding started from F1 progeny of male "SRR-Rocket Science" and a female PVG/Seac. Homozygous rats for mink were selected for inbreeding. (Sep 25, 2009)
Strain characteristics This strain has two mutations, American mink (am) which causes light brown body hair and Pearl (Pel) which causes lighter coat color and is lethal in the embryonic period if homozygous. Genetic analyses mapped am to Chr 1 (Kuramoto, 2010). A SINE insertion was identified in the exon 7 of Hermansky-Pudlak syndrome 5 (Hps5)gene (Kuramoto, 2010). (Jul 4, 2011)
Breeding Conditions Maintained by crossing of heterozygous and wild-type for Pearl mutation. This strain is heterozygous for Pearl mutation (segregating strain) and homozygous for mink mutation. Good breeding performance. (Sep 25, 2009)
References Kuramoto T, Yokoe M, Yagasaki K, Kawaguchi T, Kumafuji K, Serikawa T.
Genetic analyses of fancy rat-derived mutations.
Exp Anim. 2010;59(2):147-55.

Takashi Kuramoto, Satoshi Nakanishi, Ken-ichi Yamasaki, Kenta Kumafuji, Yuichi Sakakibara, Yuki Neoda, Akiko Takizawa, Takehito Kaneko, Mito Otsuki, Ryoko Hashimoto, Birger Voigt, Tomoji Mashimo and Tadao Serikawa
Genetic Quality Control of the Rat Strains at the National Bio Resource Project-Rat.
ibc.2010 Volume 2 Article no. 0012
Additional strain information