NBRP Rat No: 0573
Commmon Name: SRR05-Rex
Rat Genome Database
Takashi Kuramoto Graduate School of Medicine, Kyoto University Yoshidakonoe-cho, Sakyo-ku 606-8501 Kyoto Japan
Tel: 075-753-4494 Fax: 075-753-4409
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Research Area Others
One male rat "SRR Coming Home" was introduced from American fancy rat colony (Spoiled Ratten Rattery: SRR, in Kansas City, Missouri) to Kyoto University on July 13, 2005. Inbreeding started from F1 progeny of male "SRR Coming Home" and a female TM/Kyo. (Sep 25, 2009)
The rat autosomal dominant Rex (
) mutation on chromosome 7 causes curly hair in
/+ and hair loss in
rats. Histopathologically, the
/+ rat showed dilatation of the hair follicle and hairs with irregularly-coated cuticles, and the
rat showed more severe effects.
is a 7-bp deletion at the splicing acceptor site of intron 1 of the keratin 71 (
) gene. (Kuramoto, 2010) (Apr 20, 2010)
Maintained by crossing of heterozygous and homozygous for Rex gene. Good breeding performance. (Sep 25, 2009)
Kuramoto T, Hirano R, Kuwamura M, Serikawa T.
Identification of the Rat Rex Mutation as a 7-Bp Deletion at Splicing Acceptor Site of the Krt71 Gene.
J Vet Med Sci. 2010 Jul;72(7):909-12.
Kuramoto T, Yokoe M, Yagasaki K, Kawaguchi T, Kumafuji K, Serikawa T.
Genetic analyses of fancy rat-derived mutations.
Exp Anim. 2010;59(2):147-55.
Additional strain information