| NBRP Rat No: 0605 |
Strain name: AMI/Tj |
Commmon Name: |
Rat Genome Database |
| Principal Investigator: |
Taro Muto (Takafumi Noma's Lab) Institute of Health Biosciences, Tokushima University 3-15-12, Kuramoto-cho, Tokushima 770-8504 Tokushima Japan |
| Tel: 088-633-7326 Fax: 088-633-7326 |
Email: muto@dent.tokushima-u.ac.jp |
| Preservation Status: |
Embryo Sperm Living Animals |
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| Coat Color |
albino (c) |
| Inbred Generations |
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| Usage Restrictions |
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| Genetic Status |
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| Comercial Availability |
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| Research Category |
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| Gene Affected |
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| Origin |
Rats showing amelogenesis imperfecta were found in the colony of SHR-SP rats at Daiichi Seiyaku, Co., Ltd. in 1985 (Ishibashi, 1990). The SHR-SP was transferred from Kinki University Dr. Okamoto in 1981. Transferred to Tokushima University in 2003. Other name is SHRSP-ami/ami (Aug 30, 2010) |
| Strain characteristics |
AMI rats exhibit amelogenesis imperfecta due to underdevelopment of enamel-forming ameloblasts and white incisor. This phenotype is caused by an autosomal recessive gene (ami). (Ishibashi, 1990) (Aug 30, 2010) |
| Breeding Conditions |
Maintain homozygous condition by crossing AMI rats. By 20 weeks of age, breeding should be started. (Aug 30, 2010) |
| Genotyping |
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| References |
Ishibashi K, Iino T, Sekiguchi F.
Amelogenesis imperfecta, a new dental mutation in rats.
Lab Anim Sci. 1990 Jan;40(1):16-20.
Terashima T, Baba O, Takano Y, Ishibashi K, Oida S.
Analysis of enamel formation in mutant rats with hypoplastic type of amelogenesis imperfecta.
Dentistry in Japan. 2003; 39:8-14. |
| Additional strain information |
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