Strain information
 NBRP Rat No: 0605  Strain name: AMI/Tj  Commmon Name: Rat Genome Database
Principal Investigator:  Taro Muto (Takafumi Noma's Lab)  Institute of Health Biosciences, Tokushima University       3-15-12, Kuramoto-cho, Tokushima    770-8504 Tokushima     Japan
Tel: 088-633-7326    Fax: 088-633-7326 Email:
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/ ../images/Photos/
Coat Color  albino (c)
Inbred Generations  
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected
Origin Rats showing amelogenesis imperfecta were found in the colony of SHR-SP rats at Daiichi Seiyaku, Co., Ltd. in 1985 (Ishibashi, 1990). The SHR-SP was transferred from Kinki University Dr. Okamoto in 1981. Transferred to Tokushima University in 2003. Other name is SHRSP-ami/ami (Aug 30, 2010)
Strain characteristics AMI rats exhibit amelogenesis imperfecta due to underdevelopment of enamel-forming ameloblasts and white incisor. This phenotype is caused by an autosomal recessive gene (ami). (Ishibashi, 1990) (Aug 30, 2010)
Breeding Conditions Maintain homozygous condition by crossing AMI rats. By 20 weeks of age, breeding should be started. (Aug 30, 2010)
References Ishibashi K, Iino T, Sekiguchi F.
Amelogenesis imperfecta, a new dental mutation in rats.
Lab Anim Sci. 1990 Jan;40(1):16-20.

Terashima T, Baba O, Takano Y, Ishibashi K, Oida S.
Analysis of enamel formation in mutant rats with hypoplastic type of amelogenesis imperfecta.
Dentistry in Japan. 2003; 39:8-14.
Additional strain information