Strain information
 NBRP Rat No: 0614  Strain name: BN.SDT-Gluco14/Nyo  Commmon Name: BN.SDT-Gisdt2 congenic, BS2 congenic Rat Genome Database
Principal Investigator:  Norihide Yokoi  Kobe University Graduate School of Medicine       Kobe BT Center, 1-5-6, Minatojima Minami-cho, Chuo-ku, Kobe    650-0047 Hyogo     Ｊａｐａｎ
Tel: 078-304-6046    Fax: 078-304-6057 Email: yokoi@med.kobe-u.ac.jp
Preservation Status:   Embryo        Sperm       Living Animals ../images/Photos/ ../images/Photos/
Coat Color  brown (a,b,C)
Inbred Generations  N6F10 (Jul 2010)
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.The recipients shall cite the references of the resource and acknowledge the depositor as the source of the resource in the publications. Depending on the project of the recipients, a collaborative arrangement with the depositor could be required. In this case, the recipients shall discuss with the depositor.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected Gluco14 (Glucose level QTL 13), alias Gisdt2
Origin The Gluco14 (RGD ID: 631203, other name is Gisdt2) region, one of the significant QTL for glucose intolerance of SDT/Jcl was transferred onto the genetic background of BN/Seac strain. Established by speed congenic method since 2003 and afterwards maintained by sib mating (N6F10, July 2010). Please refer to STD.BN-Gluco14/Nyo (NBRP No. 0602). (Jul 14, 2010)
Strain characteristics This strain remains free from diabetes. (Jul 14, 2010)
Breeding Conditions Sib mating.
Genotyping The segment between the D2Mit18 marker (39cM) and D2Rat297 marker (129cM) is homozygous for SDT/Jcl and other chromosomal regions are homozygous for BN/Seac. (Jul 14, 2010)
References Masuyama T, Fuse M, Yokoi N, Shinohara M, Tsujii H, Kanazawa M, Kanazawa Y, Komeda K, Taniguchi K.
Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat.
Biochem Biophys Res Commun. 2003 Apr 25;304(1):196-206.
Additional strain information