NBRP Rat No: 0614 |
Strain name: BN.SDT-Gluco14/Nyo |
Commmon Name: BN.SDT-Gisdt2 congenic, BS2 congenic |
Rat Genome Database |
Principal Investigator: |
Norihide Yokoi Kobe University Graduate School of Medicine Kobe BT Center, 1-5-6, Minatojima Minami-cho, Chuo-ku, Kobe 650-0047 Hyogo Japan |
Tel: 078-304-6046 Fax: 078-304-6057 |
Email: yokoi@med.kobe-u.ac.jp |
Preservation Status: |
Embryo Sperm Living Animals |
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Coat Color |
brown (a,b,C) |
Inbred Generations |
N6F10 (Jul 2010) |
Usage Restrictions |
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.The recipients shall cite the references of the resource and acknowledge the depositor as the source of the resource in the publications. Depending on the project of the recipients, a collaborative arrangement with the depositor could be required. In this case, the recipients shall discuss with the depositor.
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Genetic Status |
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Comercial Availability |
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Research Category |
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Gene Affected |
Gluco14 (Glucose level QTL 13), alias Gisdt2 |
Origin |
The Gluco14 (RGD ID: 631203, other name is Gisdt2) region, one of the significant QTL for glucose intolerance of SDT/Jcl was transferred onto the genetic background of BN/Seac strain. Established by speed congenic method since 2003 and afterwards maintained by sib mating (N6F10, July 2010). Please refer to STD.BN-Gluco14/Nyo (NBRP No. 0602). (Jul 14, 2010) |
Strain characteristics |
This strain remains free from diabetes. (Jul 14, 2010) |
Breeding Conditions |
Sib mating. |
Genotyping |
The segment between the D2Mit18 marker (39cM) and D2Rat297 marker (129cM) is homozygous for SDT/Jcl and other chromosomal regions are homozygous for BN/Seac. (Jul 14, 2010) |
References |
Masuyama T, Fuse M, Yokoi N, Shinohara M, Tsujii H, Kanazawa M, Kanazawa Y, Komeda K, Taniguchi K.
Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat.
Biochem Biophys Res Commun. 2003 Apr 25;304(1):196-206.
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Additional strain information |
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