Strain information

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NBRP Rat No: 0600

Strain name: SD-Tg(Eno2-Vcp)16Kakiz

Commmon Name: NSE-VCP(L16)

Rat Genome Database

Principal Investigator:

Akira Kakizuka (Hori Seiji)Graduate School of BIOSTUDIES, Kyoto University

Preservation Status:

Embryo Sperm Living Animals

Coat Color

albino (c)

Inbred Generations

Usage Restrictions

The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent indicating the extent of experimental use of it from the DEPOSITOR. For a commercial use of this resource, a new contract must be concluded between the DEPOSITOR and the RECIPIENT.

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

Eno2: enolase 2, gamma, neuronal; Vcp: valosin containing protein

Origin

This transgenic strain was generated by microinjection into Slc:SD fertilized eggs. (Jun 22, 2010)

Strain characteristics

This transgenic rat overexpresses mouse VCP/p97 in the brain with rat neuron specific enolase (Eno2) promoter. (Jun 22, 2010)

Breeding Conditions

Maintained by crossing between Tg hemizygous and wild rats. (Jun 22, 2010)

Genotyping

Genotyping by PCR analysis.

References

in preparation

Additional strain information (Japanese only)