NBRP Rat No: 0601 |
Strain name: SDT.BN-Gluco13/Nyo |
Commmon Name: SDT.BN-Gisdt1 congenic, SB1 congenic |
Rat Genome Database |
Principal Investigator: |
Norihide Yokoi Kobe University Graduate School of Medicine Kobe BT Center, 1-5-6, Minatojima Minami-cho, Chuo-ku, Kobe 650-0047 Hyogo Japan |
Tel: 078-304-6046 Fax: 078-304-6057 |
Email: yokoi@med.kobe-u.ac.jp |
Preservation Status: |
Embryo Sperm Living Animals |
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Coat Color |
black hooded (a,B,C,h) |
Inbred Generations |
N9F6 (Apr 2010) |
Usage Restrictions |
The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.The recipients shall cite the references of the resource and acknowledge the depositor as the source of the resource in the publications. Depending on the project of the recipients, a collaborative arrangement with the depositor could be required. In this case, the recipients shall discuss with the depositor.
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Genetic Status |
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Comercial Availability |
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Research Category |
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Gene Affected |
Gluco13 (Glucose level QTL 13), alias Gisdt1 |
Origin |
The Gluco13 (Gisdt1) region of BN/Seac was transferred onto the genetic background of SDT/Jcl strain. Established by speed congenic method since 2003 and afterwards maintained by sib mating (N9F6, May 2010) Please refer to STD.BN-Gluco14/Nyo (NBRP No. 0602). (Jun 22, 2010) |
Strain characteristics |
All males spontaneously develop diabetes. The onset of diabetes in this strain seems to be delayed comparing with that of SDT. (Jun 22, 2010) |
Breeding Conditions |
Sib mating. |
Genotyping |
The segment between the D1Wox11 marker (57cM) and D1Rat76 marker (148cM) is homozygous for BN/Seac and other chromosomal regions are homozygous for SDT/Jcl. (Jun 22, 2010) |
References |
Masuyama T, Fuse M, Yokoi N, Shinohara M, Tsujii H, Kanazawa M, Kanazawa Y, Komeda K, Taniguchi K.
Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat.
Biochem Biophys Res Commun. 2003 Apr 25;304(1):196-206. |
Additional strain information |
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