Strain information
 NBRP Rat No: 0633  Strain name: W.GR-Ugt1a1j/Aon  Commmon Name: WGR Rat Genome Database
Principal Investigator:   Sachiko Aono  Aichi Human Service Center       713-8 Kagiyacho, Kasugai    480-0392 Aichi     JAPAN
Tel: 0568-88-0811    Fax: 0568-88-0829 Email:
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  白
Inbred Generations  SDGR:F73、WGR:F22
Usage Restrictions  In publishing, an acknowledgment to the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected Ugt1a1: UDP glucuronosyltransferase 1 family, polypeptide A1
Origin After SDGR rats were backcrossed with Wistar rats ten times, This strains were established.
Strain characteristics WGR strains having a 1 base deletion in Ugt1a1 show hyperbilirubinemia. WGR are better reproductive peformance than SDGR.
Breeding Conditions
References Sato, H., Aono, S., Kashiwamata, S. and Koiwai, O. (1991) Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat. Biochem. Biophys. Res. Commujn., 177, 1161-1164.

Keino, H., Sato, H., Semba, R., Aono, S., Aoki, E., and Kashiwamata, S. (1985-86) Mode of prevention by phototherapy of cerebellar hypoplasia in a new Sprague-Dawley strain of jaundiced Gunn rats. Peidat. Neurosci., 12, 145-150.
Additional strain information