Strain information  NBRP Rat No: 0643  Strain name: ACI.BUF-Aftm1/2Mna  Commmon Name: ACI/Mna-Aftm1 Rat Genome Database Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan Tel: 0562-93-2486    Fax: 0562-93-4008 Email: mmatsuya@fujita-hu.ac.jp Preservation Status:   Embryo        Sperm       Living Animals Coat Color  Albino Inbred Generations  F23 Usage Restrictions   Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others 軽度の速筋萎縮  Control Strain  Marker Strain Gene Affected 遺伝子領域： Aftm1 (Atrophy of fast twitch muscle-1) Origin The region of mild atrophy in fast-twitch muscles of BUF/Mna strains, was transferred onto the genetic background of ACI strain. At that time albino mutaion was also transferred because of the adjacent region. Strain characteristics All of this strain develops mild and slowly progressing muscle atrophy with absent, hypoplastic or cystic kidneys on one side in 20 %. Breeding Conditions sib mating Genotyping References Amo, H., Matsuyama, M., et al.: Genetic reguration of slowly progressing mild atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve, 20:1528-1263, 1997. Additional strain information