Strain information

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NBRP Rat No: 0643

Strain name: ACI.BUF-Aftm1/2Mna

Commmon Name: ACI/Mna-Aftm1

Rat Genome Database

Principal Investigator:

Mutsushi MatsuyamaFujita Health University

Preservation Status:

Embryo Sperm Living Animals

Coat Color

Albino

Inbred Generations

F23

Usage Restrictions

Genetic Status

Inbred Segregating Congenic Consomic Recombinant Coisogenic Spont. Mutant Transgene Ind. Mutant Category Other

Comercial Availability

Research Category

Diabetes Obesity Neurobiology Ophthalmology Dentistry Cardio Hypertension Cancer Metabolism Otorhinology Immunology Infectious Osteosis Internal Organ Dermatology Reproduction Development Behavior Hematology Urology Pharmacology Research Area Others

Control Strain Marker Strain

Gene Affected

遺伝子領域： Aftm1 (Atrophy of fast twitch muscle-1)

Origin

The region of mild atrophy in fast-twitch muscles of BUF/Mna strains, was transferred onto the genetic background of ACI strain. At that time albino mutaion was also transferred because of the adjacent region.

Strain characteristics

All of this strain develops mild and slowly progressing muscle atrophy with absent, hypoplastic or cystic kidneys on one side in 20 %.

Breeding Conditions

sib mating

Genotyping

References

Amo, H., Matsuyama, M., et al.: Genetic reguration of slowly progressing mild atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve, 20:1528-1263, 1997.

Additional strain information (Japanese only)