Strain information
 NBRP Rat No: 0643  Strain name: ACI.BUF-Aftm1/2Mna  Commmon Name: ACI/Mna-Aftm1 Rat Genome Database
Principal Investigator:  Mutsushi Matsuyama  Fujita Health University        1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi    420-1192 Aichi     Japan
Tel: 0562-93-2486    Fax: 0562-93-4008 Email:
Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  Albino
Inbred Generations  F23
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 軽度の速筋萎縮
 Control Strain  Marker Strain
Gene Affected 遺伝子領域: Aftm1 (Atrophy of fast twitch muscle-1)
Origin The region of mild atrophy in fast-twitch muscles of BUF/Mna strains, was transferred onto the genetic background of ACI strain. At that time albino mutaion was also transferred because of the adjacent region.
Strain characteristics All of this strain develops mild and slowly progressing muscle atrophy with absent, hypoplastic or cystic kidneys on one side in 20 %.
Breeding Conditions sib mating
References Amo, H., Matsuyama, M., et al.: Genetic reguration of slowly progressing mild atrophy in fast-twitch muscles of BUF/Mna rats. Muscle Nerve, 20:1528-1263, 1997.
Additional strain information