Japanese
 NBRP Rat No: 0213 Strain NameACI.BUF-Ten2/Mna Commmon Name: 
 Principal Investigator  Mutsushi Matsuyama
 Organization   Fujita Health University  Department of Virology and Parasitology
 Address  1-98 Dengakugakubo, Kutsukake-cho, Toyoake-shi

420-1192 Aichi

 Japan
 Telephone  0562-93-2486  Fax:  0562-93-4008  mmatsuya@fujita-hu.ac.jp
 Inbred Generations    
   
 Coat Color
 Deposition Status
 
 agouti
  Embryo      Sperm      Live Animals
 Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested. 
 Genetic Status   Inbred   Segregating   Congenic   Consomic    Recombinant 
  Coisogenic   Spont. Mutant    Transgene   Ind. Mutant    Others 
 Comercial Availability   
 Research Category   Diabetes Obesity    Neurobiology    Ophthalmology    Dentistry    Cardio- Hypertension 
  Oncology   Metabolism   Otorhinology    Immunology    Infectious Disease
  Osteology    Internal Medicine   Dermatology   Reproduction    Development
  Behavior    Hematology    Urology   Pharmacology   Others 
  Control Strains   Reporter gene Strains  
 Gene
 Origin This congenic strain was established as a strain with the genetic background of ACI onto which a segment from the BUF/Mna containing the thymus enlargement, <i>Ten2</i> (on Chr 13, Murakumo, 1996) has been transferred. Please refer to BUF/Mna. (Oct 12, 2010) 
 Strain Characteristics There is no data about thymus enlargement. This congenic rat develops nephrosis in 100% of animals. 
 Breeding Conditions Sib mating. 
 Genotyping  
 References  Matsuyama M, Nagayo T
Development of thymoma and myasthenia in Buffalo/Mna rats.
Proc Jpn Cancer Assoc 36th Annu Meet 30, 1977.

Murakumo Y, Takahashi M, Sharma N, Arakawa A, Saito M, Amo H, Matsuyama M.
Mapping of two genetic loci, Ten-1 and Ten-2, associated with thymus enlargement in BUF/Mna rats.
Mamm Genome. 1996 Jul;7(7):505-8.